|Application ||WB, IHC-P, FC, E|
|Other Accession||P52906, O18400, Q9I8K3, Q6QU75, Q9PWR3, Q9R0W1, P97474, Q99697, Q9W5Z2, O93385, Q9W751, Q99NA7, P70314, P56673|
|Predicted||Chicken, Mouse, Rat, Xenopus, Zebrafish, Drosophila, C.Elegans|
|Calculated MW||34128 Da|
|Antigen Region||123-150 aa|
|Other Names||Pituitary homeobox 1, Hindlimb-expressed homeobox protein backfoot, Homeobox protein PITX1, Paired-like homeodomain transcription factor 1, PITX1, BFT, PTX1|
|Target/Specificity||This PITX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-150 amino acids from the Central region of human PITX1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PITX1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Sequence-specific transcription factor that binds gene promoters and activates their transcription. May play a role in the development of anterior structures, and in particular, the brain and facies and in specifying the identity or structure of hindlimb.|
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Provided below are standard protocols that you may find useful for product applications.
PITX1 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family are involved in organ development and left-right asymmetry. This protein acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin.
Grimminger,P., Ling,F.C. Anticancer Res. 29 (4), 1281-1286 (2009)
Gurnett,C.A., Alaee,F. Am. J. Hum. Genet. 83 (5), 616-622 (2008)
Philippi,A., Tores,F. BMC Med. Genet. 8, 74 (2007)
Shang,J., Li,X. Genomics 40 (1), 108-113 (1997)
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