|Application ||WB, IHC-P, FC, E|
|Calculated MW||37394 Da|
|Antigen Region||25-54 aa|
|Other Names||Pro-cathepsin H, Cathepsin H mini chain, Cathepsin H, Cathepsin H heavy chain, Cathepsin H light chain, CTSH, CPSB|
|Target/Specificity||This CTSH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 25-54 amino acids from the N-terminal region of human CTSH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CTSH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Important for the overall degradation of proteins in lysosomes.|
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Provided below are standard protocols that you may find useful for product applications.
The protein is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of its gene has been correlated with malignant progression of prostate tumors.
Bunatova,K., Int. J. Biol. Markers 24 (1), 47-51 (2009)
Decock,J., Int. J. Biol. Markers 23 (3), 161-168 (2008)
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