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GIPR Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GIPR Antibody (N-term) AP7495A
    Western blot analysis of GIPR antibody (N-term) (Cat.#AP7495a) in HL60 cell line lysates (35ug/lane). GIPR (arrow) was detected using the purified Pab.
  • IHC-P - GIPR Antibody (N-term) AP7495A
    GIPR Antibody (N-term) (Cat. #AP7495A)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GIPR Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - GIPR Antibody (N-term) AP7495A
    GIPR Antibody (Center) (Cat. #AP7495a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P48546
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 53157 Da
Antigen Region 7-38 aa
Additional Information
Gene ID 2696
Other Names Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
Target/Specificity This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGIPR Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
Cellular Location Cell membrane; Multi-pass membrane protein.
Research Areas
Citations ( 0 )


GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.


Herbach,N. Am. J. Physiol. Renal Physiol. 296 (4), F819-F829 (2009) Rudovich,N., Kaiser,S. Regul. Pept. 142 (3), 138-145 (2007) Nitz,I., Fisher,E. Mol Nutr Food Res 51 (8), 1046-1052 (2007)

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$ 295.00
$ 99.00
Cat# AP7495A
(40 western blots)
Availability: In Stock
Bulk Size
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