|Application ||WB, E|
|Calculated MW||58763 Da|
|Antigen Region||303-334 aa|
|Other Names||Amine oxidase [flavin-containing] B, Monoamine oxidase type B, MAO-B, MAOB|
|Target/Specificity||This MAOB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 303-334 amino acids from the Central region of human MAOB.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MAOB Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.|
|Cellular Location||Mitochondrion outer membrane; Single-pass type IV membrane protein; Cytoplasmic side|
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Provided below are standard protocols that you may find useful for product applications.
MAOB belongs to the flavin monoamine oxidase family. This protein is a enzyme located in the mitochondrial outer membrane. The protein catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. The protein preferentially degrades benzylamine and phenylethylamine.
Bergen,S.E., Fanous,A.H. Schizophr. Res. 109 (1-3), 94-97 (2009)
Zhu,Q.S., Grimsby,J. J. Neurosci. 12 (11), 4437-4446 (1992)
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