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CDC7 (CDC7L1) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - CDC7 (CDC7L1) Antibody (N-term) AP7515a
    HCDC7L1 Antibody (M9) (Cat. #AP7515a) western blot analysis in HT29,MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow).
  • WB - CDC7 (CDC7L1) Antibody (N-term) AP7515a
    HCDC7L1 Antibody (M9) (Cat. #AP7515a) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the HCDC7L1 antibody detected the HCDC7L1 protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O00311
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 63888 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 8317
Other Names Cell division cycle 7-related protein kinase, CDC7-related kinase, HsCdc7, huCdc7, CDC7, CDC7L1
Target/Specificity This CDC7 (CDC7L1) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CDC7 (CDC7L1).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC7 (CDC7L1) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDC7
Synonyms CDC7L1
Function Seems to phosphorylate critical substrates that regulate the G1/S phase transition and/or DNA replication. Can phosphorylates MCM2 and MCM3.
Cellular Location Nucleus.
Research Areas
Citations (0)

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CDC7L1 is predominantly localized in the nucleus and is a cell division cycle protein with kinase activity. Although expression levels of the protein appear to be constant throughout the cell cycle, the protein kinase activity appears to increase during S phase. It has been suggested that the protein is essential for initiation of DNA replication and that it plays a role in regulating cell cycle progression. Overexpression of this gene product may be associated with neoplastic transformation for some tumors.


Montagnoli, A., et al., EMBO J. 21(12):3171-3181 (2002).
Hess, G.F., et al., Gene 211(1):133-140 (1998).
Jiang, W., et al., Proc. Natl. Acad. Sci. U.S.A. 94(26):14320-14325 (1997).
Sato, N., et al., EMBO J. 16(14):4340-4351 (1997).

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$ 295.00
$ 99.00
Cat# AP7515a
(40 western blots)
Availability: In Stock
Bulk Size
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