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AARS2 Antibody (Center)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP7559c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
- Specification
- Citiations : 0
- Reviews
- Protocols
- Backgrounds
AARS2 Antibody (Center) - Product info | |
| Application | WB, IHC, FC
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| Primary Accession | Q5JTZ9 |
| Other Accession | A2RRN5 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 107340 Da |
AARS2 Antibody (Center) - Additional info | |
| Gene ID 57505 | |
| Other Names AARS2; AARSL; KIAA1270; Alanine--tRNA ligase, mitochondrial; Alanyl-tRNA synthetase | |
| Target/Specificity This AARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 373~402 amino acids from the Center region of human AARS2. | |
| Dilution WB~~1:50~100WB~~1:1000 IHC~~1:10~50 FC~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions AARS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
AARS2 Antibody (Center) - Protein Information | |
| Name AARS2 | |
| Synonyms AARSL, KIAA1270 | |
| Function Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged tRNA(Ala) via its editing domain (By similarity) | |
| Cellular Location Mitochondrion. | |
AARS2 Antibody (Center) - Related products
AP7559b: Alanyl-tRNA synthetase 2 (AARS2) Antibody(C-term)
AP7559c: AARS2 Antibody (Center)
AARS2 Antibody (Center) - Application data
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AARS2 Antibody (Center) (Cat.#AP7559c) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the AARS2 antibody detected the AARS2 protein (arrow).
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AARS2 Antibody (Center) (Cat. #AP7559c)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AARS2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
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AARS2 Antibody (Center) (Cat. #AP7559c) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
AARS2 Antibody (Center) - Research Areas
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Provided below are standard protocols that you may find useful for product applications.
BACKGROUND
Alanyl-tRNA synthetase 2 (AARS2) is an enzyme that catalyzes the chemical reaction: ATP + L-alanine + tRNAAla <---> AMP + diphosphate + L-alanyl-tRNAAla. This enzyme participates in alanine and aspartate metabolism and aminoacyl-tRNA biosynthesis.
REFERENCES
Bonnefond,L.,Biochemistry 44 (12), 4805-4816 (2005) Nakayama,M., Genome Res. 12 (11), 1773-1784 (2002)
