|Application ||WB, E|
|Other Accession||P69849, Q5JPE7|
|Calculated MW||134324 Da|
|Antigen Region||1187-1216 aa|
|Other Names||Nodal modulator 1, pM5 protein, NOMO1, PM5|
|Target/Specificity||This NOMO1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1187-1216 amino acids from human NOMO1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||NOMO1 Antibody (S1205) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May antagonize Nodal signaling.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
|Tissue Location||Expressed in colon tumor tissue and in adjacent normal colonic mucosa|
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Provided below are standard protocols that you may find useful for product applications.
NOMO1 was originally thought to be related to the collagenase family. The gene encoding NOMO1 is one of three highly similar genes in a region of duplication located on the p arm of chromosome 16. These three genes encode closely related proteins that may have the same function. The protein encoded by one of these genes has been identified as part of a protein complex that participates in the Nodal signaling pathway during vertebrate development.
Blackshaw,S., PLoS Biol. 2 (9), E247 (2004)
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