- CITATIONS: 1
|Application ||WB, E|
|Calculated MW||48337 Da|
|Antigen Region||104-133 aa|
|Other Names||G2/mitotic-specific cyclin-B1, CCNB1, CCNB|
|Target/Specificity||This Cyclin B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-133 amino acids from human Cyclin B1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Cyclin B1 Antibody (S126) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Essential for the control of the cell cycle at the G2/M (mitosis) transition.|
|Cellular Location||Cytoplasm. Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome|
Provided below are standard protocols that you may find useful for product applications.
Cyclin B1 is a regulatory protein involved in mitosis. It complexes with p34(cdc2) to form the maturation-promoting factor (MPF).
Yoshida, T., et al., Ann. Oncol. 15(2):252-256 (2004). Chang, D.C., et al., J. Biol. Chem. 278(39):37865-37873 (2003). Sanchez, V., et al., J. Virol. 77(24):13214-13224 (2003). Li, J.Q., et al., Int. J. Oncol. 22(5):1101-1110 (2003). Porter, L.A., et al., Blood 101(5):1928-1933 (2003).
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