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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   PLTP Antibody (C-term)   

PLTP Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - PLTP Antibody (C-term) AP7620b
    Western blot analysis of PLTP antibody (C-term) (Cat.#AP7620b) in HepG2 cell line lysates (35ug/lane). PLTP (arrow) was detected using the purified Pab.
  • IHC-P - PLTP Antibody (C-term) AP7620b
    Formalin-fixed and paraffin-embedded human lung carcinoma reacted with PLTP Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - PLTP Antibody (C-term) AP7620b
    PLTP Antibody (C-term) (Cat. #AP7620b) flow cytometric analysis of HepG2 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P55058
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54739 Da
Antigen Region 451-479 aa
Additional Information
Gene ID 5360
Other Names Phospholipid transfer protein, Lipid transfer protein II, PLTP
Target/Specificity This PLTP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 451-479 amino acids from the C-terminal region of human PLTP.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPLTP Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Facilitates the transfer of a spectrum of different lipid molecules, including diacylglycerol, phosphatidic acid, sphingomyelin, phosphatidylcholine, phosphatidylglycerol, cerebroside and phosphatidyl ethanolamine. Essential for the transfer of excess surface lipids from triglyceride-rich lipoproteins to HDL, thereby facilitating the formation of smaller lipoprotein remnants, contributing to the formation of LDL, and assisting in the maturation of HDL particles. PLTP also plays a key role in the uptake of cholesterol from peripheral cells and tissues that is subsequently transported to the liver for degradation and excretion. Two distinct forms of PLTP exist in plasma: an active form that can transfer PC from phospholipid vesicles to high-density lipoproteins (HDL), and an inactive form that lacks this capability.
Cellular Location Secreted.
Tissue Location Wide tissue distribution. Placenta > pancreas > lung > kidney > heart > liver > skeletal muscle > brain
Research Areas
Citations (0)

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PLTP is one of at least two lipid transfer proteins found in human plasma. The protein transfers phospholipids from triglyceride-rich lipoproteins to high density lipoprotein (HDL). In addition to regulating the size of HDL particles, this protein may be involved in cholesterol metabolism.


Moerland,M., Samyn,H. Arterioscler. Thromb. Vasc. Biol. 28 (7), 1277-1282 (2008)
Albers,J.J., Wolfbauer,G. Biochim. Biophys. Acta 1258 (1), 27-34 (1995)

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$ 295.00
$ 99.00
Cat# AP7620b
(40 western blots)
Availability: In Stock
Bulk Size
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