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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Lactoferrin (LTF) Antibody (Center)   

Lactoferrin (LTF) Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • IHC-P - Lactoferrin (LTF) Antibody (Center) AP7647c
    Formalin-fixed and paraffin-embedded prostata carcinoma tissue reacted with LTF Antibody (Center)(Cat.#AP7647c), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • WB - Lactoferrin (LTF) Antibody (Center) AP7647c
    Western blot analysis of anti-LTF Antibody (Center) Pab (Cat.#AP7647c) in mouse heart tissue lysates (35ug/lane). LTF(arrow) was detected using the purified Pab (1:60 dilution).
  • WB - Lactoferrin (LTF) Antibody (Center) AP7647c
    Western blot analysis of anti-LTF Antibody (Center) Pab (Cat.#AP7647c) in 293 cell line lysates transiently transfected with the LTF gene (2ug/lane). LTF(arrow) was detected using the purified Pab (1:60 dilution).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P02788
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 78182 Da
Antigen Region 219-248 aa
Additional Information
Gene ID 4057
Other Names Lactotransferrin, Lactoferrin, 3421-, Growth-inhibiting protein 12, Talalactoferrin, Lactoferricin-H, Lfcin-H, Kaliocin-1, Lactoferroxin-A, Lactoferroxin-B, Lactoferroxin-C, LTF, GIG12, LF
Target/Specificity This Lactoferrin (LTF) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-248 amino acids from the Central region of human Lactoferrin (LTF).
Dilution IHC-P~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLactoferrin (LTF) Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LTF
Synonyms GIG12, LF
Function Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactoferricin binds to the bacterial surface and is crucial for the bactericidal functions. Has some antiviral activity against papillomavirus infection. N-terminal region shows strong antifungal activity against C.albicans. Contains two BBXB heparin-binding consensus sequences that appear to form the predominate functional GAG-binding site. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. Isoform DeltaLf: transcription factor with antiproliferative properties and ability to induce cell cycle arrest. Binds to the DeltaLf response element found in the SKP1, BAX, DCPS, and SELH promoters.
Cellular Location Isoform 1: Secreted. Cytoplasmic granule. Note=Secreted into most exocrine fluids by various endothelial cells. Stored in the secondary granules of neutrophils
Tissue Location High levels are found in saliva and tears, intermediate levels in serum and plasma, and low levels in urine In kidney, detected in the distal collecting tubules in the medulla but not in the cortical region or in blood vessels Detected in peripheral blood neutrophils (at protein level) Isoform 1 and isoform DeltaLf are expressed in breast, prostate, spleen, pancreas, kidney, small intestine, lung, skeletal muscle, uterus, thymus and fetal liver. Isoform 1 is expressed in brain, testis and peripheral blood leukocytes; isoform DeltaLf is barely detectable in these tissues. Isoform DeltaLf is expressed in placenta, liver and ovary; isoform 1 is barely detectable in these tissues. In kidney, isoform 1 is expressed at high levels in the collecting tubules of the medulla but at very low levels in the cortex.
Research Areas
Citations ( 0 )


This protein is a member of the transferrin family of metal-binding proteins found in milk and other secretory fluids and also in blood. It shows multifunctional properties of which the bacteriostatic and bactericidal effects are the best known.

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$ 295.00
$ 99.00
Cat# AP7647c
(40 western blots)
Availability: In Stock
Bulk Size
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