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ROR2 Antibody

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ROR2 Antibody AP7672d
    Western blot analysis of anti-ROR2 Antibody (Cat.#AP7672d) in K562 cell line lysates (35ug/lane). ROR2(arrow) was detected using the purified Pab.
  • IHC-P - ROR2 Antibody AP7672d
    Formalin-fixed and paraffin-embedded human brain tissue reacted with ROR2 antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q01974
Other Accession NP_004551
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 104757 Da
Additional Information
Gene ID 4920
Other Names Tyrosine-protein kinase transmembrane receptor ROR2, Neurotrophic tyrosine kinase, receptor-related 2, ROR2, NTRKR2
Target/Specificity This ROR2 antibody is generated from rabbits immunized with a recombinant protein of human ROR2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsROR2 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ROR2
Synonyms NTRKR2
Function Tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. Phosphorylates YWHAB, leading to induction of osteogenesis and bone formation.
Cellular Location Cell membrane; Single-pass type I membrane protein
Research Areas
Citations ( 0 )


ROR2 is a tyrosine-protein kinase receptor which may be involved in the early formation of the chondrocytes. It seems to be required for cartilage and growth plate development. This Type I membrane protein is expressed at high levels during early embryonic development. The expression levels drop strongly around day 16 and there are only very low levels in adult tissues. Defects in ROR2 are a cause of brachydactyly type B1 (BDB1). BDB1 is an autosomal dominant skeletal disorder characterized by hypoplasia/aplasia of distal phalanges and nails. In BDB1 the middle phalanges are short but in addition the terminal phalanges are rudimentary or absent. Both fingers and toes are affected. The thumbs and big toes are usually deformed. Defects in ROR2 are a cause of recessive Robinow syndrome (RRS). RRS is an autosomal disorder characterized by skeletal dysplasia with generalized limb bone shortening, segmental defects of the spine, brachydactyly and a dysmorphic facial appearance. The protein contains 1 frizzled (FZ) domain, 1 immunoglobulin-like C2-type domain, and 1 kringle domain.


Afzal, A.R., et al., Nat. Genet. 25(4):419-422 (2000). Oldridge, M., et al., Nat. Genet. 24(3):275-278 (2000). van Bokhoven, H., et al., Nat. Genet. 25(4):423-426 (2000). Schwabe, G.C., et al., Am. J. Hum. Genet. 67(4):822-831 (2000). Masiakowski, P., et al., J. Biol. Chem. 267(36):26181-26190 (1992).

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$ 295.00
$ 99.00
Cat# AP7672d
(40 western blots)
Availability: In Stock
Bulk Size
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