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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   AREG Antibody (C-term)   

AREG Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - AREG Antibody (C-term) AP7776b
    AREG Antibody (C-term) (Cat.#AP7776b) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the AREG antibody detected the AREG protein (arrow).
  • IHC-P - AREG Antibody (C-term) AP7776b
    AREG Antibody (C-term) (Cat. #AP7776b)immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of AREG Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P15514
Other Accession NP_001648
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 27895 Da
Antigen Region 222-252 aa
Additional Information
Gene ID 374
Other Names Amphiregulin, AR, Colorectum cell-derived growth factor, CRDGF, AREG, SDGF
Target/Specificity This AREG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 222-252 amino acids from the C-terminal region of human AREG.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsAREG Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms SDGF
Function Ligand of the EGF receptor/EGFR. Autocrine growth factor as well as a mitogen for a broad range of target cells including astrocytes, Schwann cells and fibroblasts.
Cellular Location Membrane; Single-pass membrane protein.
Research Areas
Citations (0)

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AREG is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes, Schwann cells, and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This protein is associated with a psoriasis-like skin phenotype.


Shim,J.Y., J. Korean Med. Sci. 23 (5), 857-863 (2008)
Eckstein,N., J. Biol. Chem. 283 (2), 739-750 (2008)
Revillion,F., Ann. Oncol. 19 (1), 73-80 (2008)
Kimura,H., Nature 348 (6298), 257-260 (1990)

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Cat# AP7776b
(40 western blots)
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