|Application ||WB, IHC-P, E|
|Calculated MW||58283 Da|
|Antigen Region||315-344 aa|
|Other Names||Serine--tRNA ligase, mitochondrial, SerRSmt, Seryl-tRNA synthetase, SerRS, Seryl-tRNA(Ser/Sec) synthetase, SARS2, SARSM|
|Target/Specificity||This SARS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-344 amino acids from the Central region of human SARS2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SARS2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec) (By similarity).|
|Cellular Location||Mitochondrion matrix.|
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Provided below are standard protocols that you may find useful for product applications.
SARS2 catalyzes the attachment of serine to tRNA(Ser). It is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).
Muller,T., Acta Neuropathol. 110 (4), 426-430 (2005)
Gibbons,W.J. Jr., Biochem. Biophys. Res. Commun. 317 (3), 774-778 (2004)
Yokogawa,T., J. Biol. Chem. 275 (26), 19913-19920 (2000)
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