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CDC25C Antibody (C-term)Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP7862b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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CDC25C Antibody (C-term) - Product info | |
| Application | WB
|
| Primary Accession | P30307 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 53365 Da |
CDC25C Antibody (C-term) - Additional info | |
| Gene ID 995 | |
| Other Names CDC25C; M-phase inducer phosphatase 3; Dual specificity phosphatase Cdc25C | |
| Target/Specificity This CDC25C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 381~411 amino acids from the C-terminal region of human CDC25C. | |
| Dilution WB~~1:50~100WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions CDC25C Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
CDC25C Antibody (C-term) - Protein Information | |
| Name CDC25C | |
| Function Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity | |
| Cellular Location Nucleus. | |
CDC25C Antibody (C-term) - Related products
AM1908a: CDC25C Antibody (ascites)
AP7862b: CDC25C Antibody (C-term)
AP7862d: CDC25C Antibody (Center)
RI10921: CDC25C predesign siRNA
DC04797: Human CDC25C cDNA Clone
LY11518a: CDC25C Over-expression Lysate
BP7862b: CDC25C Antibody (C-term) Blocking Peptide
BP7862d: CDC25C Antibody (Center) Blocking Peptide
AT1458a: CDC25C Antibody (monoclonal) (M01)
CDC25C Antibody (C-term) - Application data
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Western blot analysis of anti-CDC25C Antibody (C-term) (Cat.#AP7862b) in K562 cell line lysates (35ug/lane).CDC25C(arrow) was detected using the purified Pab.
CDC25C Antibody (C-term) - Research Areas
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BACKGROUND
CDC25C is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest.
REFERENCES
Varmeh,S., Mol. Cancer Ther. 7 (12), 3789-3799 (2008) Long,J.M., Cell Cycle 7 (19), 3062-3073 (2008) Bonnet,J., Cell Cycle 7 (13), 1991-1998 (2008)