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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CYP4A11 (4A22) Antibody (C-term)   

CYP4A11 (4A22) Antibody (C-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYP4A11 (4A22) Antibody (C-term) AP7884b
    Western blot analysis of anti-CYP4A11 (4A22) Antibody (C-term) (Cat.#AP7884b) in NCI-H460 cell line lysates (35ug/lane).CYP4A11(arrow) was detected using the purified Pab.
  • IF - CYP4A11 (4A22) Antibody (C-term) AP7884b
    Confocal immunofluorescent analysis of CYP4A11 (4A22) Antibody (C-term)(Cat#AP7884b) with NCI-H460 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green).DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q02928
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59348 Da
Antigen Region 407-435 aa
Additional Information
Gene ID 1579
Other Names Cytochrome P450 4A11, 20-hydroxyeicosatetraenoic acid synthase, 20-HETE synthase, CYP4AII, CYPIVA11, Cytochrome P-450HK-omega, Cytochrome P450HL-omega, Fatty acid omega-hydroxylase, Lauric acid omega-hydroxylase, CYP4A11, CYP4A2
Target/Specificity This CYP4A11 (4A22) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-435 amino acids from the C-terminal region of human CYP4A11 (4A22).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYP4A11 (4A22) Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP4A11
Synonyms CYP4A2
Function Catalyzes the omega- and (omega-1)-hydroxylation of various fatty acids such as laurate, myristate and palmitate. Has little activity toward prostaglandins A1 and E1. Oxidizes arachidonic acid to 20-hydroxyeicosatetraenoic acid (20-HETE).
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Kidney and liver.
Research Areas
Citations (0)

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CYP4A11 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and hydroxylates medium-chain fatty acids such as laurate and myristate.


Sugimoto,K., Hypertension 52 (6), 1142-1148 (2008)
Ward,N.C., Hypertension 51 (5), 1393-1398 (2008)
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)

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$ 295.00
$ 99.00
Cat# AP7884b
(40 western blots)
Availability: In Stock
Bulk Size
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