|Application ||WB, IHC-P, E|
|Calculated MW||58875 Da|
|Antigen Region||157-183 aa|
|Other Names||Cytochrome P450 4X1, CYPIVX1, CYP4X1|
|Target/Specificity||This CYP4X1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 157-183 amino acids from the N-terminal region of human CYP4X1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CYP4X1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Endoplasmic reticulum membrane; Single-pass membrane protein Microsome membrane|
|Tissue Location||Expressed in brain, heart and kidney and, at lower levels, in skeletal muscle and liver. In the heart, very high level levels in aorta, but very levels in other heart regions.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
CYP4X1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. The expression pattern of a similar rat protein suggests that this protein may be involved in neurovascular function in the brain.
Savas,U., Arch. Biochem. Biophys. 436 (2), 377-385 (2005)
Nelson,D.R., Pharmacogenetics 14 (1), 1-18 (2004)
Bylund,J., Biochem. Biophys. Res. Commun. 296 (3), 677-684 (2002)
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