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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   CYP3A43 Antibody (Center)   

CYP3A43 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CYP3A43 Antibody (Center) AP7999c
    Anti-CYP3A43 Antibody (Center) at 1:2000 dilution + HepG2 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 58 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • FC - CYP3A43 Antibody (Center) AP7999c
    CYP3A43 Antibody (Center) (Cat. #AP7999c) flow cytometry analysis of 293 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
  • IF - CYP3A43 Antibody (Center) AP7999c
    Confocal immunofluorescent analysis of CYP3A43 Antibody (Center)(Cat#AP7999c) with 293 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9HB55
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 57670 Da
Antigen Region 242-270 aa
Additional Information
Gene ID 64816
Other Names Cytochrome P450 3A43, CYP3A43
Target/Specificity This CYP3A43 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 242-270 amino acids from the Central region of human CYP3A43.
Dilution WB~~1:2000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCYP3A43 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CYP3A43
Function Exhibits low testosterone 6-beta-hydroxylase activity.
Cellular Location Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein
Tissue Location Highest expression level in prostate. Also expressed in liver, kidney, pancreas, fetal liver and fetal skeletal muscle.
Research Areas
Citations (0)

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CYP3A43 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein has a low level of testosterone hydroxylase activity. Although it bears homology to some drug-metabolizing cytochrome P450s, the protein unknown whether the enzyme is also involved in xenobiotic metabolism.


Domanski T.L., Finta C.Mol. Pharmacol. 59:386-392(2001)
Westlind A., Malmebo S.Biochem. Biophys. Res. Commun. 281:1349-1355(2001)
Cauffiez C., Lo-Guidice J.-M.Hum. Mutat. 23:101-101(2004)

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$ 295.00
$ 99.00
Cat# AP7999c
(40 western blots)
Availability: In Stock
Bulk Size
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