|Application ||WB, E|
|Other Accession||P25157, Q6Q7Y5, P27601, Q14344, Q63210, P27600, Q5YKG4|
|Predicted||Mouse, Rat, Drosophila|
|Calculated MW||44279 Da|
|Antigen Region||46-75 aa|
|Other Names||Guanine nucleotide-binding protein subunit alpha-12, G alpha-12, G-protein subunit alpha-12, GNA12|
|Target/Specificity||This GNA12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from human GNA12.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GNA12 Antibody (S67) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. May play a role in the control of cell migration through the TOR signaling cascade.|
|Cellular Location||Membrane; Lipid-anchor.|
firstname.lastname@example.org, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Guanine nucleotide-binding proteins (G proteins) are modulators or transducers in various transmembrane signaling systems. G proteins are composed of 3 subunits; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Krakstad, B.F., et al., Proc. Natl. Acad. Sci. U.S.A. 101(28):10314-10319 (2004).
Hillier, L.W., et al., Nature 424(6945):157-164 (2003).
Scherer, S.W., et al., Science 300(5620):767-772 (2003).
Suzuki, N., et al., Proc. Natl. Acad. Sci. U.S.A. 100(2):733-738 (2003).
Yamaguchi, Y., et al., J. Biol. Chem. 278(17):14936-14939 (2003).
If you have any additional inquiries please email technical services at email@example.com.