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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KIST (KIS) Antibody (N-term)   

KIST (KIS) Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - KIST (KIS) Antibody (N-term) AP8067a
    Western blot analysis of anti-KIS Pab (Cat. #AP8067a) in mouse heart tissue lysate. KIS (arrow) was detected using purified Pab. Secondary HRP-anti-rabbit was used for signal visualization with chemiluminescence.
  • IHC-P - KIST (KIS) Antibody (N-term) AP8067a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
  • WB - KIST (KIS) Antibody (N-term) AP8067a
    KIS Antibody (C6) (Cat. #AP8067a) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the KIS antibody detected the KIS protein (arrow).
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8TAS1
Other Accession Q63285, P97343
Reactivity Human, Mouse
Predicted Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 46546 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 127933
Other Names Serine/threonine-protein kinase Kist, Kinase interacting with stathmin, PAM COOH-terminal interactor protein 2, P-CIP2, U2AF homology motif kinase 1, UHMK1, KIS, KIST
Target/Specificity This KIST (KIS) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human KIST (KIS).
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsKIST (KIS) Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name UHMK1
Synonyms KIS, KIST
Function Upon serum stimulation, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. May be involved in trafficking and/or processing of RNA (By similarity).
Cellular Location Nucleus.
Tissue Location Widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes
Research Areas
Citations ( 0 )


Upon serum stimulation, KIS, a member of the Ser/Thr protein kinase family, phosphorylates CDKN1B/p27Kip1, thus controlling CDKN1B subcellular location and cell cycle progression in G1 phase. This protein, which contains 1 RRM (RNA recognition motif)domain, may be involved in trafficking and/or processing of RNA. KIS is widely expressed, with highest levels in skeletal muscle, kidney, placenta and peripheral blood leukocytes.


Bieche, I., et al., Brain Res. Mol. Brain Res. 114(1):55-64 (2003).
Boehm, M., et al., EMBO J. 21(13):3390-3401 (2002).

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$ 295.00
$ 99.00
Cat# AP8067a
(40 western blots)
Availability: In Stock
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