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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   MOS Antibody (N-term)   

MOS Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - MOS Antibody (N-term) AP8069a
    Western blot analysis of anti-MOS-R8 Pab (Cat. #AP8069a) in 293 and Hela cell line lysate (35ug/lane). MOS-R8(arrow) was detected using the purified Pab.
  • WB - MOS Antibody (N-term) AP8069a
    Western blot analysis of MOS (arrow) using rabbit polyclonal hMOS-R8 (Cat. #AP8069a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the MOS gene (Lane 2) (Origene Technologies).
  • IHC-P - MOS Antibody (N-term) AP8069a
    Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P00540
Other Accession NP_005363
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 37820 Da
Antigen Region 1-30 aa
Additional Information
Gene ID 4342
Other Names Proto-oncogene serine/threonine-protein kinase mos, Oocyte maturation factor mos, Proto-oncogene c-Mos, MOS
Target/Specificity This MOS antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human MOS.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsMOS Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MOS
Tissue Location Expressed specifically in testis during spermatogenesis
Research Areas
Citations (0)

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Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.


Caubet, J.F., et al., EMBO J. 4(9):2245-2248 (1985).
Watson, R., et al., Proc. Natl. Acad. Sci. U.S.A. 79(13):4078-4082 (1982).
Singh, B., et al., Prog Cell Cycle Res 3, 251-259 (1997).

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$ 295.00
$ 99.00
Cat# AP8069a
(40 western blots)
Availability: In Stock
Bulk Size
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