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ITPKB Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ITPKB Antibody (N-term) AP8167a
    Western blot analysis of ITPKB (arrow) using rabbit polyclonal ITPKB Antibody (R38) (Cat. #AP8167a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the ITPKB gene.
  • IHC-P - ITPKB Antibody (N-term) AP8167a
    ITPKB Antibody (N-term) (Cat. #AP8167a)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of ITPKB Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - ITPKB Antibody (N-term) AP8167a
    ITPKB Antibody (N-term) (Cat. #AP8167a) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P27987
Other Accession NP_002212
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 102376 Da
Antigen Region 23-54 aa
Additional Information
Gene ID 3707
Other Names Inositol-trisphosphate 3-kinase B, Inositol 1, 5-trisphosphate 3-kinase B, IP3 3-kinase B, IP3K B, InsP 3-kinase B, ITPKB
Target/Specificity This ITPKB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 23-54 amino acids from the N-terminal region of human ITPKB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITPKB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Research Areas
Citations (0)

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ITPKB regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1,4,5-trisphosphate to Ins(1,3,4,5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.


Dewaste, V., et al., Biochem. Biophys. Res. Commun. 291(2):400-405 (2002).
Woodring, P.J., et al., J. Biol. Chem. 272(48):30447-30454 (1997).
Erneux, C., et al., Genomics 14(2):546-547 (1992).
Takazawa, K., et al., Biochem. J. 272(1):107-112 (1990).
Takazawa, K., et al., Biochem. J. 278 (PT 3), 883-886 (1991) (): ().

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$ 295.00
$ 99.00
Cat# AP8167a
(40 western blots)
Availability: In Stock
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