|Application ||WB, IHC-P, E|
|Other Accession||Q63665, Q64705|
|Calculated MW||36955 Da|
|Antigen Region||218-246 aa|
|Other Names||Upstream stimulatory factor 2, Class B basic helix-loop-helix protein 12, bHLHb12, FOS-interacting protein, FIP, Major late transcription factor 2, Upstream transcription factor 2, USF2, BHLHB12|
|Target/Specificity||This USF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human USF2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||USF2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5'-CACGTG-3') that is found in a variety of viral and cellular promoters.|
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Provided below are standard protocols that you may find useful for product applications.
USF2 is a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. This protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs.
Olsen,J.V., et.al., Cell 127 (3), 635-648 (2006)
Groenen,P.M., et.al., Genomics 38 (2), 141-148 (1996)
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