|Application ||WB, IHC-P, FC, E|
|Other Accession||P07896, Q9DBM2|
|Calculated MW||79495 Da|
|Antigen Region||662-690 aa|
|Other Names||Peroxisomal bifunctional enzyme, PBE, PBFE, Enoyl-CoA hydratase/3, 2-trans-enoyl-CoA isomerase, 3-hydroxyacyl-CoA dehydrogenase, EHHADH, ECHD|
|Target/Specificity||This EHHADH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 662-690 amino acids from the C-terminal region of human EHHADH.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||EHHADH Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Liver and kidney. Strongly expressed in the terminal segments of the proximal tubule. Lower amounts seen in the brain.|
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Provided below are standard protocols that you may find useful for product applications.
EHHADH is a bifunctional enzyme and is one of the four enzymes of the peroxisomal beta-oxidation pathway. The N-terminal region of the encoded protein contains enoyl-CoA hydratase activity while the C-terminal region contains 3-hydroxyacyl-CoA dehydrogenase activity.
Chen,G.L., et.al., Biochem. Biophys. Res. Commun. 178 (3), 1084-1091 (1991)
Lu,Y., et.al., J. Lipid Res. 49 (12), 2582-2589 (2008)
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