|Application ||WB, IHC-P, FC, E|
|Calculated MW||26301 Da|
|Antigen Region||140-167 aa|
|Other Names||Tetraspanin-1, Tspan-1, Tetraspan NET-1, Tetraspanin TM4-C, TSPAN1|
|Target/Specificity||This TSPAN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-167 amino acids from the Central region of human TSPAN1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TSPAN1 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Cellular Location||Lysosome membrane; Multi-pass membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
TSPAN1 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
Xu,D., et.al., FASEB J. 23 (11), 3674-3681 (2009)
Berditchevski,F.et.al., J. Cell. Sci. 114 (PT 23), 4143-4151 (2001)
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