|Application ||WB, IHC-P, E|
|Calculated MW||65976 Da|
|Antigen Region||133-161 aa|
|Other Names||Zinc finger protein GLIS1, GLI-similar 1, GLIS1 (HGNC:29525)|
|Target/Specificity||This GLIS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 133-161 amino acids from the N-terminal region of human GLIS1.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GLIS1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as both a repressor and activator of transcription. Binds to the consensus sequence 5'-GACCACCCAC-3' (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
GLIS1 is a GLI (MIM 165220)-related Kruppel-like zinc finger protein that functions as an activator and repressor of transcription (Kim et al., 2002 [PubMed 12042312]).
Kim,Y.S., et.al., Nucleic Acids Res. 31 (19), 5513-5525 (2003)
Nakanishi,G., et.al., J. Invest. Dermatol. 126 (1), 49-60 (2006)
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