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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   GC Antibody (Center)   

GC Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - GC Antibody      (Center) AP8937C
    Western blot analysis of GC Antibody (Center) (Cat. #AP8937c) in mouse lung tissue lysates (35ug/lane). GC (arrow) was detected using the purified Pab.
  • IHC-P - GC Antibody      (Center) AP8937C
    Formalin-fixed and paraffin-embedded human Skin reacted with GC Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - GC Antibody      (Center) AP8937C
    GC Antibody (Center) (Cat. #AP8937c) flow cytometric analysis of NCI-H460 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P04062
Other Accession Q70KH2, Q2KHZ8
Reactivity Human, Mouse
Predicted Pig, Bovine
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 59716 Da
Antigen Region 337-365 aa
Additional Information
Gene ID 2629
Other Names Glucosylceramidase, Acid beta-glucosidase, Alglucerase, Beta-glucocerebrosidase, Beta-GC, D-glucosyl-N-acylsphingosine glucohydrolase, Imiglucerase, GBA, GC, GLUC
Target/Specificity This GC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the Central region of human GC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGC Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GBA
Synonyms GC, GLUC
Cellular Location Lysosome membrane; Peripheral membrane protein; Lumenal side. Note=Interaction with saposin-C promotes membrane association. Targeting to lysosomes occurs through an alternative MPR-independent mechanism via SCARB2
Research Areas
Citations (0)

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GC is a protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism.


Jamrozik,Z.,, J. Neurol. 257 (3), 459-460 (2010)
Mao,X.Y.,, Neurosci. Lett. 469 (2), 256-259 (2010)

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Cat# AP8937C
(40 western blots)
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