|Application ||WB, FC, E|
|Other Accession||P19814, Q62314, Q62313|
|Calculated MW||51113 Da|
|Antigen Region||399-427 aa|
|Other Names||Trans-Golgi network integral membrane protein 2, TGN38 homolog, TGN46, TGN48, Trans-Golgi network protein TGN51, TGOLN2, TGN46, TGN51|
|Target/Specificity||This TGOLN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 399-427 amino acids from the C-terminal region of human TGOLN2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TGOLN2 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in regulating membrane traffic to and from trans-Golgi network.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane; Single- pass type I membrane protein. Note=Primarily in trans-Golgi network. Cycles between the trans-Golgi network and the cell surface returning via endosomes|
|Tissue Location||Isoform TGN46 is widely expressed. Isoform TGN51 is more abundant in fetal lung and kidney. Isoform TGN48 is barely expressed in embryonic kidney and promyelocytic cells|
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Provided below are standard protocols that you may find useful for product applications.
TGOLN2 may be involved in regulating membrane traffic to and from trans-Golgi network.
Wu,C., et.al., Proteomics 7 (11), 1775-1785 (2007)
Honing,S., et.al., Mol. Cell 18 (5), 519-531 (2005)
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