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LY75 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - LY75 Antibody (Center) AP8994c
    Western blot analysis of LY75 Antibody (Center) (Cat. #AP8994c) in HL-60 cell line lysates (35ug/lane). LY75 (arrow) was detected using the purified Pab.
  • IHC-P - LY75 Antibody (Center) AP8994c
    Formalin-fixed and paraffin-embedded human spleen tissue reacted with LY75 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - LY75 Antibody (Center) AP8994c
    LY75 Antibody (Center) (Cat. #AP8994c) flow cytometric analysis of HL-60 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60449
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 198311 Da
Antigen Region 646-675 aa
Additional Information
Gene ID 100526664;4065
Other Names Lymphocyte antigen 75, Ly-75, C-type lectin domain family 13 member B, DEC-205, gp200-MR6, CD205, LY75, CD205, CLEC13B
Target/Specificity This LY75 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 646-675 amino acids from the Central region of human LY75.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsLY75 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name LY75
Synonyms CD205, CLEC13B
Function Acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen- processing compartment (By similarity). Causes reduced proliferation of B-lymphocytes.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Expressed in spleen, thymus, colon and peripheral blood lymphocytes. Detected in myeloid and B-lymphoid cell lines. Isoform 2 and isoform 3 are expressed in malignant Hodgkin lymphoma cells called Hodgkin and Reed-Sternberg (HRS) cells.
Research Areas
Citations (0)

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LY75 acts as an endocytic receptor to direct captured antigens from the extracellular space to a specialized antigen-processing compartment. It causes reduced proliferation of B-lymphocytes.


Kato,M.,, Immunogenetics 47 (6), 442-450 (1998)
McKay,P.F.,, Eur. J. Immunol. 28 (12), 4071-4083 (1998)

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$ 295.00
$ 99.00
Cat# AP8994c
(40 western blots)
Availability: In Stock
Bulk Size
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