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>   home   >   Products   >   Primary Antibodies   >   Cell Biology   >   CDC2L6 Antibody (Center)   

CDC2L6 Antibody (Center)

Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - CDC2L6 Antibody (Center) AP9082c
    Western blot analysis of CDC2L6 Antibody (Center) (Cat. #AP9082c) in mouse heart tissue lysates (35ug/lane). CDC2L6 (arrow) was detected using the purified Pab.
  • IHC-P - CDC2L6 Antibody (Center) AP9082c
    Formalin-fixed and paraffin-embedded human brain tissue reacted with CDC2L6 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - CDC2L6 Antibody (Center) AP9082c
    CDC2L6 Antibody (Center) (Cat. #AP9082c) flow cytometric analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, FC, E
Primary Accession Q9BWU1
Other Accession Q8BWD8
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 56802 Da
Antigen Region 253-285 aa
Additional Information
Gene ID 23097
Other Names Cyclin-dependent kinase 19, CDC2-related protein kinase 6, Cell division cycle 2-like protein kinase 6, Cell division protein kinase 19, Cyclin-dependent kinase 11, Death-preventing kinase, CDK19, CDC2L6, CDK11, KIAA1028
Target/Specificity This CDC2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-285 amino acids from the Central region of human CDC2L6.
Dilution WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCDC2L6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name CDK19
Synonyms CDC2L6, CDK11, KIAA1028
Research Areas
Citations (0)

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Background

CDC2L6 is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.

References

Malumbres,M., et.al. Nat. Cell Biol. 11 (11), 1275-1276 (2009)
Loyer,P., et.al., J. Biol. Chem. 283 (12), 7721-7732 (2008)

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Cat# AP9082c
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(40 western blots)
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