|Application ||WB, IHC-P, FC, E|
|Calculated MW||56802 Da|
|Antigen Region||253-285 aa|
|Other Names||Cyclin-dependent kinase 19, CDC2-related protein kinase 6, Cell division cycle 2-like protein kinase 6, Cell division protein kinase 19, Cyclin-dependent kinase 11, Death-preventing kinase, CDK19, CDC2L6, CDK11, KIAA1028|
|Target/Specificity||This CDC2L6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 253-285 amino acids from the Central region of human CDC2L6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.|
|Precautions||CDC2L6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CDC2L6, CDK11, KIAA1028|
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Provided below are standard protocols that you may find useful for product applications.
CDC2L6 is one of the components of the Mediator coactivator complex. The Mediator complex is a multiprotein complex required for transcriptional activation by DNA binding transcription factors of genes transcribed by RNA polymerase II. The protein encoded by this gene is similar to cyclin-dependent kinase 8 which can also be a component of the Mediator complex.
Malumbres,M., et.al. Nat. Cell Biol. 11 (11), 1275-1276 (2009)
Loyer,P., et.al., J. Biol. Chem. 283 (12), 7721-7732 (2008)
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