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HSPCB Antibody (N-term)

Purified Rabbit Polyclonal Antibody (Pab)

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  • WB - HSPCB Antibody (N-term) AP9087a
    Anti-HSPCB Antibody (N-term) at 1:1000 dilution + A431 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 83 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - HSPCB Antibody (N-term) AP9087a
    HSPCB Antibody (N-term) (Cat.# AP9087a) western blot analysis in A431,H-4-II-E,Hela,rat L6 cell line lysates (35ug/lane).This demonstrates the HSPCB antibody detected the HSPCB protein (arrow).
  • IHC-P - HSPCB Antibody (N-term) AP9087a
    Formalin-fixed and paraffin-embedded human testis tissue reacted with HSPCB Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P08238
Other Accession P34058, P11499, Q4R4T5, Q76LV1, Q58FF7, Q58FF8, Q9GKX8
Reactivity Human
Predicted Bovine, Monkey, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 83264 Da
Antigen Region 42-74 aa
Additional Information
Gene ID 3326
Other Names Heat shock protein HSP 90-beta, HSP 90, Heat shock 84 kDa, HSP 84, HSP84, HSP90AB1, HSP90B, HSPC2, HSPCB
Target/Specificity This HSPCB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 42-74 amino acids from the N-terminal region of human HSPCB.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHSPCB Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSP90AB1
Synonyms HSP90B, HSPC2, HSPCB
Function Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Cellular Location Cytoplasm. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
Research Areas
Citations (0)

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HSPCB proteins are highly conserved molecular chaperones that have key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSPCB proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress.


Chadli,A.,, J. Biol. Chem. 285 (6), 4224-4231 (2010)
Zhang,T.,, J. Biol. Chem. 284 (51), 35381-35389 (2009)

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$ 295.00
$ 99.00
Cat# AP9087a
(40 western blots)
Availability: In Stock
Bulk Size
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