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ADRBK2 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ADRBK2 Antibody (N-term) AP9092a
    Western blot analysis of ADRBK2 (arrow) using rabbit polyclonal ADRBK2 Antibody (N-term) (Cat. #AP9092a). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the ADRBK2 gene (Lane 2) .
  • IHC-P - ADRBK2 Antibody (N-term) AP9092a
    Formalin-fixed and paraffin-embedded human brain tissue reacted with ADRBK2 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P35626
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 79710 Da
Antigen Region 29-57 aa
Additional Information
Gene ID 157
Other Names Beta-adrenergic receptor kinase 2, Beta-ARK-2, G-protein-coupled receptor kinase 3, ADRBK2, BARK2, GRK3
Target/Specificity This ADRBK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 29-57 amino acids from the N-terminal region of human ADRBK2.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsADRBK2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms BARK2, GRK3
Function Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors.
Research Areas
Citations (0)

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ADRBK2 is the beta-adrenergic receptor kinase specifically phosphorylates the agonist-occupied form of the beta-adrenergic and related G protein-coupled receptors. Overall, the beta adrenergic receptor kinase 2 has 85% amino acid similarity with beta adrenergic receptor kinase 1, with the protein kinase catalytic domain having 95% similarity. These data suggest the existence of a family of receptor kinases which may serve broadly to regulate receptor function.


Gratacos,M.,, Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)
Rao,J.S.,, Int. J. Neuropsychopharmacol. 12 (6), 851-860 (2009)

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Cat# AP9092a
(40 western blots)
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