|Application ||WB, IHC-P, FC, E|
|Calculated MW||44928 Da|
|Antigen Region||132-158 aa|
|Other Names||Killer cell immunoglobulin-like receptor 3DL3, CD158 antigen-like family member Z, Killer cell inhibitory receptor 1, CD158z, KIR3DL3, CD158Z, KIR3DL7, KIRC1|
|Target/Specificity||This KIR3DL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 132-158 amino acids from the Central region of human KIR3DL3.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KIR3DL3 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CD158Z, KIR3DL7, KIRC1|
|Function||Receptor on natural killer cells. May inhibit the activity of NK cells thus preventing cell lysis.|
|Cellular Location||Cell membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
KIR3DL3 is transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. This protein are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC).
Trompeter,H.I., et.al., J. Immunol. 174 (7), 4135-4143 (2005)
Arnheim,L., et.al., Tissue Antigens 65 (3), 252-259 (2005)
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