|Application ||WB, IHC-P, FC, E|
|Other Accession||Q8CGU9, Q8CGV2, Q0EAB8|
|Calculated MW||56057 Da|
|Antigen Region||168-193 aa|
|Other Names||Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2, TPH2, NTPH|
|Target/Specificity||This TPH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 168-193 amino acids from the Central region of human TPH2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TPH2 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Tissue Location||Brain specific.|
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Provided below are standard protocols that you may find useful for product applications.
This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
Khatua,A.K., et.al., Virology 400 (1), 68-75 (2010)
Koning,F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)
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