|Application ||WB, IHC-P, FC, E|
|Calculated MW||93518 Da|
|Antigen Region||375-403 aa|
|Other Names||Complement component C7, C7|
|Target/Specificity||This C7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-403 amino acids from the Central region of human C7.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||C7 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Constituent of the membrane attack complex (MAC) that plays a key role in the innate and adaptive immune response by forming pores in the plasma membrane of target cells. C7 serves as a membrane anchor.|
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Provided below are standard protocols that you may find useful for product applications.
C7 is a component of the complement system. It participates in the formation of Membrane Attack Complex (MAC). People with C7 deficiency are prone to bacterial infection.
Davila,S., et.al., Genes Immun. 11 (3), 232-238 (2010)
Kuijpers,T.W., et.al., Mol. Immunol. 47 (4), 671-677 (2010)
Wheeler,H.E., et.al., PLoS Genet. 5 (10), E1000685 (2009)
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