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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   XDH Antibody (N-term)   

XDH Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - XDH Antibody (N-term) AP9277A
    Anti-XDH Antibody (N-term) at 1:1000 dilution + human fetal liver lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 146 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - XDH Antibody (N-term) AP9277A
    Western blot analysis of XDH Antibody (N-term) (Cat. #AP9277a) in mouse lung tissue lysates (35ug/lane). XDH (arrow) was detected using the purified Pab.
  • IHC-P - XDH Antibody (N-term) AP9277A
    Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with XDH Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - XDH Antibody (N-term) AP9277A
    XDH Antibody (N-term) (Cat. #AP9277a) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47989
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 146424 Da
Antigen Region 206-234 aa
Additional Information
Gene ID 7498
Other Names Xanthine dehydrogenase/oxidase, Xanthine dehydrogenase, XD, Xanthine oxidase, XO, Xanthine oxidoreductase, XOR, XDH, XDHA
Target/Specificity This XDH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-234 amino acids from the N-terminal region of human XDH.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsXDH Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name XDH
Synonyms XDHA
Function Key enzyme in purine degradation. Catalyzes the oxidation of hypoxanthine to xanthine. Catalyzes the oxidation of xanthine to uric acid. Contributes to the generation of reactive oxygen species. Has also low oxidase activity towards aldehydes (in vitro).
Cellular Location Cytoplasm. Peroxisome. Secreted
Tissue Location Detected in milk (at protein level). {ECO:0000269|Ref.12}
Research Areas
Citations (0)

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XDH belongs to the group of molybdenum-containing hydroxylases involved in the oxidative metabolism of purines. The enzyme is a homodimer. This protein can be converted to xanthine oxidase by reversible sulfhydryl oxidation or by irreversible proteolytic modification. Defects in xanthine dehydrogenase cause xanthinuria, may contribute to adult respiratory stress syndrome, and may potentiate influenza infection through an oxygen metabolite-dependent mechanism.


Ross,C.J.,, Nat. Genet. 41 (12), 1345-1349 (2009)
Taibi,G.,, J. Cell. Biochem. 108 (3), 688-692 (2009)
Spiekermann,S.,, Eur. Respir. J. 34 (1), 276 (2009)

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$ 295.00
$ 99.00
Cat# AP9277A
(40 western blots)
Availability: In Stock
Bulk Size
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