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ABCF1 Antibody (C-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP9278b | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9278b-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ABCF1 Antibody (C-term) - Product info | |
| Application | WB, IHC
|
| Primary Accession | Q8NE71 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 95926 Da |
ABCF1 Antibody (C-term) - Additional info | |
| Gene ID 23 | |
| Other Names ABCF1; ABC50; ATP-binding cassette sub-family F member 1; ATP-binding cassette 50; TNF-alpha-stimulated ABC protein | |
| Target/Specificity This ABCF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 694~724 amino acids from the C-terminal region of human ABCF1. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ABCF1 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ABCF1 Antibody (C-term) - Protein Information | |
| Name ABCF1 | |
| Synonyms ABC50 | |
| Function Isoform 2 is required for efficient Cap- and IRES- mediated mRNA translation initiation. Isoform 2 is not involved in the ribosome biogenesis | |
| Cellular Location Isoform 2: Cytoplasm. Nucleus, nucleoplasm. Nucleus envelope | |
| Tissue Location Ubiquitous. | |
ABCF1 Antibody (C-term) - Related products
AP9278b: ABCF1 Antibody (C-term)
ABCF1 Antibody (C-term) - Application data
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Western blot analysis of ABCF1 Antibody (C-term)(Cat. #AP9278b) in NCI-H460 cell line lysates (35ug/lane). ABCF1 (arrow) was detected using the purified Pab.
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Western blot analysis of ABCF1 Antibody (C-term)(Cat. #AP9278b) in mouse NIH-3T3 cell line lysates (35ug/lane). ABCF1 (arrow) was detected using the purified Pab.
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ABCF1 Antibody (C-term) (Cat. #AP9278b) IHC analysis in formalin fixed and paraffin embedded human testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the ABCF1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
ABCF1 Antibody (C-term) - Research Areas
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BACKGROUND
The protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC proteins are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the GCN20 subfamily. Unlike other members of the superfamily, this protein lacks the transmembrane domains which are characteristic of most ABC transporters. This protein may be regulated by tumor necrosis factor-alpha and play a role in enhancement of protein synthesis and the inflammation process.
REFERENCES
Barcellos,L.F., et.al., PLoS Genet. 5 (10), E1000696 (2009) Paytubi,S., et.al., J. Biol. Chem. 284 (36), 24061-24073 (2009) Saito,A., et.al., J. Hum. Genet. 54 (6), 317-323 (2009)