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SNRPD3 Antibody (C-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - SNRPD3 Antibody (C-term) AP9280b
    Western blot analysis of SNRPD3 Antibody (C-term) (Cat. #AP9280b) in MCF-7, Jurkat cell line lysates (35ug/lane). SNRPD3 (arrow) was detected using the purified Pab.
  • IHC-P - SNRPD3 Antibody (C-term) AP9280b
    SNRPD3 Antibody (C-term) (Cat. #AP9280b) IHC analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SNRPD3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
  • FC - SNRPD3 Antibody (C-term) AP9280b
    SNRPD3 Antibody (C-term) (Cat. #AP9280b) flow cytometric analysis of MCF-7 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P62318
Other Accession P62323, P62320
Reactivity Human
Predicted Mouse, Xenopus
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 13916 Da
Antigen Region 99-126 aa
Additional Information
Gene ID 6634
Other Names Small nuclear ribonucleoprotein Sm D3, Sm-D3, snRNP core protein D3, SNRPD3
Target/Specificity This SNRPD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 99-126 amino acids from the C-terminal region of human SNRPD3.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsSNRPD3 Antibody (C-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Core component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs. Most spliceosomal snRNPs contain a common set of Sm proteins SNRPB, SNRPD1, SNRPD2, SNRPD3, SNRPE, SNRPF and SNRPG that assemble in an heptameric protein ring on the Sm site of the small nuclear RNA to form the core snRNP. As part of the U7 snRNP it is involved in histone 3'-end processing.
Cellular Location Cytoplasm, cytosol. Nucleus. Note=SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes
Citations ( 0 )


The protein belongs to the small nuclear ribonucleoprotein core protein family. It is required for pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis.


Gonsalvez,G.B.,, J. Cell Biol. 178 (5), 733-740 (2007)
Ma,Y.,, Structure 13 (6), 883-892 (2005)
Mahler,M.,, Arthritis Res. Ther. 7 (1), R19-R29 (2005)

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$ 295.00
$ 99.00
Cat# AP9280b
(40 western blots)
Availability: In Stock
Bulk Size
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