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ITPKC Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - ITPKC Antibody (N-term) AP9326A
    Western blot analysis of ITPKC Antibody (N-term) (Cat. #AP9326a) in HepG2 cell line lysates (35ug/lane). ITPKC (arrow) was detected using the purified Pab.
  • IHC-P - ITPKC Antibody (N-term) AP9326A
    Formalin-fixed and paraffin-embedded human skeletal muscle reacted with ITPKC Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - ITPKC Antibody (N-term) AP9326A
    ITPKC Antibody (N-term) (Cat. #AP9326a) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q96DU7
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 75207 Da
Antigen Region 89-117 aa
Additional Information
Gene ID 80271
Other Names Inositol-trisphosphate 3-kinase C, Inositol 1, 5-trisphosphate 3-kinase C, IP3 3-kinase C, IP3K C, InsP 3-kinase C, ITPKC, IP3KC
Target/Specificity This ITPKC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-117 amino acids from the N-terminal region of human ITPKC.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsITPKC Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms IP3KC
Function Can phosphorylate inositol 2,4,5-triphosphate to inositol 2,4,5,6-tetraphosphate.
Cellular Location Nucleus. Cytoplasm. Note=Shuttles actively between nucleus and cytoplasm with both nuclear import and nuclear export activity
Tissue Location Highly expressed in pancreas, skeletal muscle, liver, placenta and weakly in kidney and brain
Research Areas
Citations (0)

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ITPKC encodes a member of the inositol 1,4,5-trisphosphate [Ins(1,4,5)P(3)] 3-kinase family of enzymes that catalyze the phosphorylation of inositol 1,4,5-trisphosphate to 1,3,4,5-tetrakisphosphate. The encoded protein is localized to the nucleus and cytoplasm and has both nuclear import and nuclear export activity. Single nucleotide polymorphisms in this gene are associated with Kawasaki disease.


Chi,H. Hum. Mol. Genet. 19 (6), 1147-1151 (2010)
Onouchi,Y. Nat. Genet. 40 (1), 35-42 (2008)
Nalaskowski,M.M. Biol. Chem. 387 (5), 583-593 (2006)

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$ 295.00
$ 99.00
Cat# AP9326A
(40 western blots)
Availability: In Stock
Bulk Size
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