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S39A8 Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - S39A8 Antibody (Center) AP9359c
    Western blot analysis of S39A8 Antibody (Center) (Cat. #AP9359c) in CEM cell line lysates (35ug/lane). S39A8 (arrow) was detected using the purified Pab.
  • FC - S39A8 Antibody (Center) AP9359c
    S39A8 Antibody (Center) (Cat. #AP9359c) flow cytometric analysis of CEM cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9C0K1
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 49631 Da
Antigen Region 218-246 aa
Additional Information
Gene ID 64116
Other Names Zinc transporter ZIP8, BCG-induced integral membrane protein in monocyte clone 103 protein, LIV-1 subfamily of ZIP zinc transporter 6, LZT-Hs6, Solute carrier family 39 member 8, Zrt- and Irt-like protein 8, ZIP-8, SLC39A8, BIGM103, ZIP8
Target/Specificity This S39A8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 218-246 amino acids from the Central region of human S39A8.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsS39A8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC39A8
Synonyms BIGM103, ZIP8
Function Acts as a zinc-influx transporter.
Cellular Location Membrane; Multi-pass membrane protein. Note=Associated with the lysosomal/endosomal compartment following transfection
Tissue Location Expressed in thymus, placenta, lung, liver, pancreas and, to a lower extent, in spleen, testis, ovary, small intestine, colon, leukocyte, heart. Highest expression is observed in pancreas.
Research Areas
Citations (0)

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S39A8 encodes a member of the SLC39 family of solute-carrier genes, which show structural characteristics of zinc transporters. The encoded protein is glycosylated and found in the plasma membrane and mitochondria, and functions in the cellular import of zinc at the onset of inflammation. It is also thought to be the primary transporter of the toxic cation cadmium, which is found in cigarette smoke.


Wang,L. Cancer Epidemiol. Biomarkers Prev. 17 (12), 3558-3566 (2008)
Aiba,I. Mol. Pharmacol. 74 (3), 823-833 (2008)
Besecker,B. Am. J. Physiol. Lung Cell Mol. Physiol. 294 (6), L1127-L1136 (2008)

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Cat# AP9359c
(40 western blots)
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