|Application ||WB, IHC-P, FC, E|
|Calculated MW||28835 Da|
|Antigen Region||81-108 aa|
|Other Names||Transmembrane protein 150A, Transmembrane protein 150, TMEM150A, TMEM150|
|Target/Specificity||This T150A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human T150A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||T150A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex (PubMed:25608530). Acts as a regulator of phosphatidylinositol 4- phosphate (PtdIns(4)P) synthesis (PubMed:25608530). May also play a role in fasting-induced catabolism (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures (PubMed:25608530)|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
T150A is possible role in fasting-induced catabolism.
Zhang,J. Biochim. Biophys. Acta 1492 (1), 280-284 (2000)
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