|Application ||WB, IHC-P, FC, E|
|Calculated MW||28835 Da|
|Antigen Region||81-108 aa|
|Other Names||Transmembrane protein 150A, Transmembrane protein 150, TMEM150A, TMEM150|
|Target/Specificity||This T150A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 81-108 amino acids from the Central region of human T150A.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||T150A Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates localization of phosphatidylinositol 4-kinase (PI4K) to the plasma membrane, possibly by reducing the association of TTC7 (TTC7A or TTC7B) with the PI4K complex (PubMed:25608530). Acts as a regulator of phosphatidylinositol 4- phosphate (PtdIns(4)P) synthesis (PubMed:25608530). May also play a role in fasting-induced catabolism (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Note=Localizes mainly at the plasma membrane; only a minor fraction localizes on intracellular structures (PubMed:25608530)|
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Provided below are standard protocols that you may find useful for product applications.
T150A is possible role in fasting-induced catabolism.
Zhang,J. Biochim. Biophys. Acta 1492 (1), 280-284 (2000)
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