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ACP1 Antibody (N-term)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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| Catalog # | Size | Availability | Price | |
| AP9411a | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9411a-ev20 | 20 ug 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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- Citiations : 0
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ACP1 Antibody (N-term) - Product info | |
| Application | WB, IHC, FC, IF
|
| Primary Accession | P24666 |
| Reactivity | Human |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 18042 Da |
ACP1 Antibody (N-term) - Additional info | |
| Gene ID 52 | |
| Other Names ACP1; Low molecular weight phosphotyrosine protein phosphatase; Adipocyte acid phosphatase; Low molecular weight cytosolic acid phosphatase; Red cell acid phosphatase 1 | |
| Target/Specificity This ACP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 40~69 amino acids from the N-terminal region of human ACP1. | |
| Dilution WB~~1:100~500WB~~1:1000 IHC~~1:50~100 FC~~1:10~50 IF~~1:10~50 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACP1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACP1 Antibody (N-term) - Protein Information | |
| Name ACP1 | |
| Function Acts on tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Isoform 3 does not possess phosphatase activity | |
| Cellular Location Cytoplasm. | |
| Tissue Location T-lymphocytes express only isoform 2. | |
ACP1 Antibody (N-term) - Related products
ACP1 Antibody (N-term) - Application data
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Western blot analysis of ACP1 Antibody (N-term) (Cat. #AP9411a) in Hela cell line lysates (35ug/lane). ACP1 (arrow) was detected using the purified Pab.
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Formalin-fixed and paraffin-embedded human brain tissue reacted with ACP1 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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ACP1 Antibody (N-term) (Cat. #AP9411a) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
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Confocal immunofluorescent analysis of ACP1 Antibody (N-term)(Cat#AP9411a) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
ACP1 Antibody (N-term) - Research Areas
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BACKGROUND
ACP1 belongs to the phosphotyrosine protein phosphatase family of proteins. It functions as an acid phosphatase and a protein tyrosine phosphatase by hydrolyzing protein tyrosine phosphate to protein tyrosine and orthophosphate. This enzyme also hydrolyzes orthophosphoric monoesters to alcohol and orthophosphate. This gene is genetically polymorphic, and three common alleles segregating at the corresponding locus give rise to six phenotypes. Each allele appears to encode at least two electrophoretically different isozymes, Bf and Bs, which are produced in allele-specific ratios.
REFERENCES
Saccucci, P., et al. Med. Sci. Monit. 15 (10), CR511-CR517 (2009) : Shu, Y.H., et al. J. Clin. Endocrinol. Metab. 94(10):4094-4102(2009) Apelt, N., et al. Metab. Clin. Exp. 58(10):1415-1423(2009) Banci, M., et al. Cardiology 113(4):236-242(2009) Rousseff, R.T., et al. Neuropediatrics 39(6):354-356(2008)
