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DBC1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - DBC1 Antibody (N-term) AP9464a
    Western blot analysis of DBC1 Antibody (N-term) (Cat. #AP9464a) in mouse heart tissue lysates (35ug/lane). DBC1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60477
Other Accession Q925T8, Q920P3, Q7ZZR3, Q5E9L2
Reactivity Human, Mouse
Predicted Bovine, Chicken, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 88760 Da
Antigen Region 85-111 aa
Additional Information
Gene ID 1620
Other Names BMP/retinoic acid-inducible neural-specific protein 1, Deleted in bladder cancer protein 1, BRINP1, DBC1, DBCCR1, FAM5A
Target/Specificity This DBC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 85-111 amino acids from the N-terminal region of human DBC1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDBC1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DBC1, DBCCR1, FAM5A
Function Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
Cellular Location Cytoplasm.
Tissue Location Highly expressed in brain. Weakly expressed in heart, lung, skeletal muscle, kidney, thymus, prostate, testis and small intestine.
Research Areas
Citations (0)

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DBC1 is located within a chromosomal region that shows loss of heterozygosity in some bladder cancers. It contains a 5' CpG island that may be a frequent target of hypermethylation, and it may undergo hypermethylation-based silencing in some bladder cancers.


Koyama, S., et al. Biochem. Biophys. Res. Commun. 392(3):357-362(2010)
Gronbaek, K., et al. Mod. Pathol. 21(5):632-638(2008)
Louhelainen, J.P., et al. Oncogene 25(16):2409-2419(2006)
Izumi, H., et al. Hum. Mol. Genet. 14(8):997-1007(2005)
Beetz, C., et al. Oncol. Rep. 13(2):335-340(2005)
Nishiyama, H., et al. Oncogene 20(23):2956-2964(2001)

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$ 295.00
$ 99.00
Cat# AP9464a
(40 western blots)
Availability: In Stock
Bulk Size
Seasonal Special on Bulk Order
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