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C11orf30 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

     
  • WB - C11orf30 Antibody (N-term) AP9475a
    Anti-C11orf30 Antibody (N-term) at 1:1000 dilution + MCF-7 whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 141 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - C11orf30 Antibody (N-term) AP9475a
    Anti-C11orf30 Antibody (N-term) at 1:2000 dilution + mouse brain lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 141 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
  • WB - C11orf30 Antibody (N-term) AP9475a
    Western blot analysis of C11orf30 Antibody (N-term) (Cat. #AP9475a) in Ramos cell line lysates (35ug/lane). C11orf30 (arrow) was detected using the purified Pab.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q7Z589
Other Accession Q8BMB0, Q7ZUV7
Reactivity Human
Predicted Zebrafish, Mouse
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 141468 Da
Antigen Region 46-75 aa
Additional Information
Gene ID 56946
Other Names Protein EMSY, EMSY, C11orf30
Target/Specificity This C11orf30 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-75 amino acids from the N-terminal region of human C11orf30.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsC11orf30 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name EMSY (HGNC:18071)
Synonyms C11orf30
Function Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2. As part of a histone H3-specific methyltransferase complex may mediate ligand-dependent transcriptional activation by nuclear hormone receptors.
Cellular Location Nucleus. Note=Localizes to DNA damage markers in irradiated cells, suggesting that it participates in DNA repair process
Citations (0)

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Background

Regulator which is able to repress transcription, possibly via its interaction with a multiprotein chromatin remodeling complex that modifies the chromatin. Its interaction with BRCA2 suggests that it may play a central role in the DNA repair function of BRCA2.

References

?Esparza-Gordillo, J., et al. Nat. Genet. 41(5):596-601(2009)
?Garapaty, S., et al. J. Biol. Chem. 284(12):7542-7552(2009)
?Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009)
?Vega, A., et al. Gynecol. Oncol. 112(1):210-214(2009)

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$ 295.00
$ 99.00
Cat# AP9475a
Size:
Quantity:
(40 western blots)
Availability: In Stock
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