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ACAD8 Antibody (Center)Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
| Country | United States
Ordering Information
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|---|---|---|---|---|
| Catalog # | Size | Availability | Price | |
| AP9488c | 0.1 mg 400 ul | In Stock | $ 255.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
| AP9488c-ev20 | Ev20 size 100 ul | In Stock | $ 95.00 | DISCONTINED INQUIRE CLICK INQUIRE Add to cart |
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ACAD8 Antibody (Center) - Product info | |
| Application | WB
|
| Primary Accession | Q9UKU7 |
| Other Accession | Q9D7B6 |
| Reactivity | Human, Mouse |
| Concentration | 0.25 mg/ml |
| Isotype | Rabbit Ig |
| Calculated MW | 45070 Da |
ACAD8 Antibody (Center) - Additional info | |
| Gene ID 27034 | |
| Other Names ACAD8; ARC42; IBD; Isobutyryl-CoA dehydrogenase, mitochondrial; Activator-recruited cofactor 42 kDa component; Acyl-CoA dehydrogenase family member 8 | |
| Target/Specificity This ACAD8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125~154 amino acids from the Central region of human ACAD8. | |
| Dilution WB~~1:100~500WB~~1:1000 | |
| Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. | |
| Storage Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | |
| Precautions ACAD8 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. | |
ACAD8 Antibody (Center) - Protein Information | |
| Name ACAD8 | |
| Synonyms ARC42, IBD | |
| Function Has very high activity toward isobutyryl-CoA. Is an isobutyryl-CoA dehydrogenase that functions in valine catabolism Plays a role in transcriptional coactivation within the ARC complex | |
| Cellular Location Mitochondrion. | |
| Tissue Location Detected at comparable levels in all tissues examined (heart, lung, brain, skeletal muscle, pancreas and placenta). Weakly expressed in liver and kidney | |
ACAD8 Antibody (Center) - Related products
AP9488c: ACAD8 Antibody (Center)
ACAD8 Antibody (Center) - Application data
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Western blot analysis of ACAD8 Antibody (Center) (Cat. #AP9488c) in mouse stomach tissue lysates (35ug/lane). ACAD8 (arrow) was detected using the purified Pab.
ACAD8 Antibody (Center) - Research Areas
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BACKGROUND
ACAD8 is a member of the acyl-CoA dehydrogenase family of enzymes that catalyze the dehydrogenation of acyl-CoA derivatives in the metabolism of fatty acids or branch chained amino acids. This protein is a mitochondrial enzyme that functions in catabolism of the branched-chain amino acid valine.
REFERENCES
Wollmer, M.A., et al. Neurogenetics 8(3):179-188(2007) Ma, J., et al. Atherosclerosis 191(1):63-72(2007) Battaile, K.P., et al. J. Biol. Chem. 279(16):16526-16534(2004)