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TNFRSF10D Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TNFRSF10D Antibody (Center) AP9526c
    Western blot analysis of TNFRSF10D Antibody (Center) (Cat. #AP9526c) in HL-60 cell line lysates (35ug/lane). TNFRSF10D (arrow) was detected using the purified Pab.
  • FC - TNFRSF10D Antibody (Center) AP9526c
    TNFRSF10D Antibody (Center) (Cat. #AP9526c) flow cytometry analysis of Hela cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9UBN6
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 41823 Da
Antigen Region 252-278 aa
Additional Information
Gene ID 8793
Other Names Tumor necrosis factor receptor superfamily member 10D, Decoy receptor 2, DcR2, TNF-related apoptosis-inducing ligand receptor 4, TRAIL receptor 4, TRAIL-R4, TRAIL receptor with a truncated death domain, CD264, TNFRSF10D, DCR2, TRAILR4, TRUNDD
Target/Specificity This TNFRSF10D antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 252-278 amino acids from the Central region of human TNFRSF10D.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTNFRSF10D Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Receptor for the cytotoxic ligand TRAIL. Contains a truncated death domain and hence is not capable of inducing apoptosis but protects against TRAIL-mediated apoptosis. Reports are contradictory with regards to its ability to induce the NF- kappa-B pathway. According to PubMed:9382840, it cannot but according to PubMed:9430226, it can induce the NF-kappa-B pathway.
Cellular Location Membrane; Single-pass type I membrane protein
Tissue Location Widely expressed, in particular in fetal kidney, lung and liver, and in adult testis and liver. Also expressed in peripheral blood leukocytes, colon and small intestine, ovary, prostate, thymus, spleen, pancreas, kidney, lung, placenta and heart
Research Areas
Citations (0)

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TNFRSF is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain, a transmembrane domain, and a truncated cytoplamic death domain. This receptor does not induce apoptosis, and has been shown to play an inhibitory role in TRAIL-induced cell apoptosis.


Davila, S., et al. Genes Immun. (2010) In press :
Pei, G.T., et al. Biochem. Biophys. Res. Commun. 391(2):1274-1279(2010)
Lucas, H., et al. J. Dent. Res. 89(1):29-33(2010)
Hosgood, H.D. III, et al. Occup Environ Med 66(12):848-853(2009)
Chen, B., et al. Spine 34 (19), E677-E681 (2009) :

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$ 295.00
$ 99.00
Cat# AP9526c
(40 western blots)
Availability: In Stock
Bulk Size
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