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TAT Antibody (Center)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, FC, IHC-P, E |
|---|---|
| Primary Accession | P17735 |
| Other Accession | P04694, Q8QZR1, Q58CZ9, NP_000344 |
| Reactivity | Human, Mouse |
| Predicted | Bovine, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Calculated MW | 50399 Da |
| Antigen Region | 279-306 aa |
| Gene ID | 6898 |
|---|---|
| Other Names | Tyrosine aminotransferase, TAT, L-tyrosine:2-oxoglutarate aminotransferase, TAT |
| Target/Specificity | This TAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the Central region of human TAT. |
| Dilution | WB~~1:2000 IHC-P~~1:10~50 FC~~1:10~50 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TAT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TAT |
|---|---|
| Function | Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
TAT is a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate.
References
Liu, S., et al. Biosci. Rep. 29(2):103-109(2009)
Pasternack, S.M., et al. Br. J. Dermatol. 160(3):704-706(2009)
Maydan, G., et al. J. Inherit. Metab. Dis. 29(5):620-626(2006)
Charfeddine, C., et al. Mol. Genet. Metab. 88(2):184-191(2006)
Baharvand, H., et al. Int. J. Dev. Biol. 50(7):645-652(2006)
Natt, E., et al. Proc. Natl. Acad. Sci. U.S.A. 89(19):9297-9301(1992)
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