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TAT Antibody (Center)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - TAT Antibody (Center) AP9533C
    Western blot analysis of TAT Antibody (Center) (Cat. #AP9533c) in K562 cell line lysates (35ug/lane). TAT (arrow) was detected using the purified Pab.
  • IHC-P - TAT Antibody (Center) AP9533C
    Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with TAT Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
  • FC - TAT Antibody (Center) AP9533C
    TAT Antibody (Center) (Cat. #AP9533c) flow cytometry analysis of K562 cells (bottom histogram) compared to a negative control cell (top histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P17735
Other Accession P04694, Q8QZR1, Q58CZ9, NP_000344
Reactivity Human
Predicted Bovine, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 50399 Da
Antigen Region 279-306 aa
Additional Information
Gene ID 6898
Other Names Tyrosine aminotransferase, TAT, L-tyrosine:2-oxoglutarate aminotransferase, TAT
Target/Specificity This TAT antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 279-306 amino acids from the Central region of human TAT.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTAT Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name TAT
Function Transaminase involved in tyrosine breakdown. Converts tyrosine to p-hydroxyphenylpyruvate. Can catalyze the reverse reaction, using glutamic acid, with 2-oxoglutarate as cosubstrate (in vitro). Has much lower affinity and transaminase activity towards phenylalanine.
Research Areas
Citations (0)

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TAT is a mitochondrial protein tyrosine aminotransferase which is present in the liver and catalyzes the conversion of L-tyrosine into p-hydroxyphenylpyruvate.


Liu, S., et al. Biosci. Rep. 29(2):103-109(2009)
Pasternack, S.M., et al. Br. J. Dermatol. 160(3):704-706(2009)
Maydan, G., et al. J. Inherit. Metab. Dis. 29(5):620-626(2006)
Charfeddine, C., et al. Mol. Genet. Metab. 88(2):184-191(2006)
Baharvand, H., et al. Int. J. Dev. Biol. 50(7):645-652(2006)
Natt, E., et al. Proc. Natl. Acad. Sci. U.S.A. 89(19):9297-9301(1992)

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Cat# AP9533C
(40 western blots)
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