|Application ||WB, E|
|Calculated MW||78580 Da|
|Antigen Region||31-60 aa|
|Other Names||Acetyl-coenzyme A synthetase, cytoplasmic, Acetate--CoA ligase, Acetyl-CoA synthetase, ACS, AceCS, Acyl-CoA synthetase short-chain family member 2, Acyl-activating enzyme, ACSS2, ACAS2|
|Target/Specificity||This ACSS2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 31-60 amino acids from the N-terminal region of human ACSS2.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ACSS2 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Activates acetate so that it can be used for lipid synthesis or for energy generation.|
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Provided below are standard protocols that you may find useful for product applications.
ACSS2 is a cytosolic enzyme that catalyzes the activation of acetate for use in lipid synthesis and energy generation. The protein acts as a monomer and produces acetyl-CoA from acetate in a reaction that requires ATP.
Yun, M., et al. J. Nucl. Med. 50(8):1222-1228(2009)
Lu, Y., et al. J. Lipid Res. 49(12):2582-2589(2008)
Sugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)
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