|Application ||WB, E|
|Calculated MW||24989 Da|
|Antigen Region||103-129 aa|
|Other Names||Protein DGCR6, DiGeorge syndrome critical region 6, DGCR6|
|Target/Specificity||This DGCR6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-129 amino acids from the Central region of human DGCR6.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DGCR6 Antibody (Center) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May play a role in neural crest cell migration into the third and fourth pharyngeal pouches.|
|Cellular Location||Nucleus. Note=Predominantly nuclear|
|Tissue Location||Found in all tissues examined with highest expression in liver, heart and skeletal muscle. Lower levels in pancreas and placenta. Weak expression in brain|
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Provided below are standard protocols that you may find useful for product applications.
DGCR6 may play a role in neural crest cell migration into the third and fourth pharyngeal pouches.
Zunner, D., et al. Biochem. Biophys. Res. Commun. 393(2):185-189(2010)
Pfuhl, T., et al. Hum. Genet. 117(1):70-80(2005)
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