|Application ||WB, E|
|Other Accession||P56812, Q2HJH9, NP_004699|
|Calculated MW||14285 Da|
|Antigen Region||1-30 aa|
|Other Names||Programmed cell death protein 5, TF-1 cell apoptosis-related protein 19, Protein TFAR19, PDCD5, TFAR19|
|Target/Specificity||This PDCD5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDCD5.|
|Format||Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.|
|Storage||Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||PDCD5 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function in the process of apoptosis.|
|Tissue Location||Widely expressed. Highest levels in heart, testis, kidney, pituitary gland, adrenal gland and placenta|
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Provided below are standard protocols that you may find useful for product applications.
PDCD5 is a protein expressed in tumor cells during apoptosis independent of the apoptosis-inducing stimuli. Prior to apoptosis induction, this protein is distributed in both the nucleus and cytoplasm. Once apoptosis is induced, the level of this protein increases and by relocation from the cytoplasm, it accumulates in the nucleus. Although its exact function is not defined, this protein is thought to play an early and universal role in apoptosis.
Du, Y.J., et al. Chin. Med. Sci. J. 24(4):241-245(2009)
Young, R.P., et al. Postgrad Med J 85(1008):515-524(2009)
Salvi, M., et al. Biochem. Biophys. Res. Commun. 387(3):606-610(2009)
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