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CBAA1 Antibody (N-term)

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

  • WB - CBAA1 Antibody (N-term) AP9682a
    Western blot analysis of CBAA1 Antibody (N-term) (Cat. #AP9682a) in K562 cell line lysates (35ug/lane). CBAA1 (arrow) was detected using the purified Pab.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9BPX6
Other Accession Q4R518
Reactivity Human
Predicted Monkey
Host Rabbit
Clonality Polyclonal
Isotype Rabbit Ig
Calculated MW 54351 Da
Antigen Region 52-81 aa
Additional Information
Gene ID 10367
Other Names Calcium uptake protein 1, mitochondrial, Atopy-related autoantigen CALC, ara CALC, Calcium-binding atopy-related autoantigen 1, Hom s 4, MICU1, CALC, CBARA1
Target/Specificity This CBAA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 52-81 amino acids from the N-terminal region of human CBAA1.
Dilution WB~~1:1000
Format Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
StorageMaintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsCBAA1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name MICU1
Synonyms CALC, CBARA1
Function Key regulator of mitochondrial calcium uniporter (MCU) required to increase calcium uptake by MCU when cytoplasmic calcium is high. MICU1 and MICU2 form a disulfide-linked heterodimer that stimulate and inhibit MCU activity, respectively. MICU1 acts as a stimulator of MCU that senses calcium level via its EF-hand domains: enhances MCU opening at high Ca(2+) concentration, allowing a rapid response of mitochondria to Ca(2+) signals generated in the cytoplasm. Regulates glucose-dependent insulin secretion in pancreatic beta-cells by regulating mitochondrial calcium uptake. Induces T-helper 1-mediated autoreactivity, which is accompanied by the release of IFNG.
Cellular Location Mitochondrion inner membrane; Peripheral membrane protein. Mitochondrion intermembrane space Note=Localizes at the outer surface of the mitochondrion inner membrane
Tissue Location Expressed in epithelial cell lines. Strongly expressed in epidermal keratinocytes and dermal endothelial cells
Research Areas
Citations (0)

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Bordicchia, M., et al. Metab. Clin. Exp. (2009) In press :
Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)
Natter, S., et al. FASEB J. 12(14):1559-1569(1998)

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$ 295.00
$ 99.00
Cat# AP9682a
(40 western blots)
Availability: In Stock
Bulk Size
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